Pycnogenol alleviated adverse effects in cancer patients, Pycnogenol improved working memory in older adults, Pycnogenol lowered the use of analgesic drugs in dysmenorrhea (severe menstrual pain), Pycnogenol reduced symptoms in endometriosis comparable to leuprorelin, the standard drug for this condition, Pycnogenol was found to be effective for sun-caused hyperpigmented skin, Pycnogenol reduced the inflammation in lupus patients, Pycnogenol reduced gingival bleeding and plaque formation. Our goal is to not have a single piece of inaccurate information on this website. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. Researchers suggest that Pycnogenol may reduce cough, night-awakenings, improve airway flow, and the need for additional asthma medication [16]. Another group of men who took just l-arginine didnt improve [66]. A study of 68 people found that Pycnogenol, started 2 days prior to flying, may reduce the duration of jet lag symptoms [83]. Pycnogenol may stimulate the immune system. Andrographis is a medicinal herb used to treat many health conditions, such as the common cold, osteoarthritis, and ulcerative colitis. Talk to your own doctor about Pycnogenol if youre interested in using it for your own health. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. There are also several other natural ADHD remedies you can try. Required fields are marked *. For allergies: 50 milligrams twice daily. Two doses of 100 mg of Pycnogenol were taken two to three hours before flights and two additional capsules taken six hours later then one capsule the next day. One way to add some extra flavor and nutrients to your day is by adding prune juice to your diet. What Are These Tiny Red Spots on My Skin (Petechiae)? Pine bark extract can help reduce muscle soreness and may help improve conditions relating to poor circulation, high blood pressure, osteoarthritis, diabetes, ADHD, female reproductive issues, skin, erectile dysfunction, eye disease and sports stamina. ( 1) 2. One study found that Pycnogenol may reduce the activity of the inflammatory enzymes COX1 and COX2, similar to how NSAID drugs work. 10 Ways to Control Blood Sugar without Medication, Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies, Reduces leaky blood vessels by making the wall proteins (collagen, elastin) more resistant to damage, Helps maintain high vitamin C and E blood levels for their antioxidant effects, Inhibits platelet aggregation like low-dose aspirin, Reduces hardening in the arteries by increasing nitric oxide production in blood vessels, leading to greater dilatation, Counteracts the damaging effects of ultraviolet radiation, Stimulates the immune system by boosting T and B cell functions, Protects brain cells from toxic chemicals. In another trial, 30 people with type 2 diabetes received a range of pycnogenol doses. In 19 smokers, increased platelet aggregation was more significantly reduced by 200 mg than either 10 mg or 100 mg of Pycnogenol. but is for informational and educational purposes alone. Known for its antioxidant properties, Pycnogenol offers a wide range of potential health benefits. Regulations set manufacturing standards for supplements, but that does not guarantee that they are safe or effective. In one study, people with high blood pressure were examined to see how the supplement impacted their blood pressure. New studies show Pycnogenol can prevent or reverse the oxidative damage that produces blood vessel disease 4, metabolic syndrome 20, diabetes 20,24, and neurodegenerative disorders 23,24. Pycnogenol has been shown to help relieve the pain associated with osteoarthritis by keeping blood chemicals from attacking the cartilage. Diabetes-associated small blood vessel changes is the leading cause of diabetic ulcers. 3. is a clickable link to peer-reviewed scientific studies. A high number signals high blood pressure. Pycnogenol French maritime pine bark extract's 4 basic properties. Add to Cart. Symptoms include swelling in ankles and legs, discolored skin and, if the skin is broken, the development of leg ulcers. Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. Pycnogenol is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins . DOI: Luzzi R, et al. Next, the doctors discuss the link between salt and hypertension, and Dr. Steve gives his insight on drinking red wine for a healthy heart. You can find out your systolic blood pressure by looking at the top number of a blood pressure test. (2004). The combination of L-arginine and Pycnogenol may help in erectile dysfunction by boosting nitric oxide, which potentially could improve blood flow in men [66]. According to a meta-analysis of 9 trials including 549 people, 150-200 mg/day for at least 12 weeks may reduce both diastolic and systolic blood pressure [36]. Fundukian, L.J. In another good study, 48 patients with diabetes and high blood pressure on ACE inhibitors were randomized to receive either Pycnogenol 125 mg daily or placebo for 12 weeks. A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [20]. A 2017 review reported on the many benefits of using pine bark extract to reduce the effects of aging on skin. DOI: Marini A, et al. SelfDecode is a personalized health report service, All of our content is written by scientists and people with a strong science background. Early research shows that taking it at least 5 weeks before the start of allergy season seems to lessen symptoms. Cigarette smoking increases platelet aggregation. Studies have found that when taken along with an inhaler, Pycnogenol can reduce leukotrienes, helping to relieve lung inflammation and limit frequency of inhaler use., Many people develop osteoarthritis as they age. Pycnogenol is similar to grape seed extract and cocoa polyphenols as those are the three most common . The Benefits of DIM. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [emailprotected]. Herbal supplements are not regulated by the Food and Drug Administration (FDA), so they may not be up to the same safety standards as medications that have gone through clinical testing and drug trials. Interesting activities, new dishes in restaurants, specialty ingredients, explanations of some netizens questions, etc.Hu Xuan is even helping Fatty s company s tourism manager, managing with Vice President Du Meixin, such as arranging guests reasonably.By the way.Dad, I want to tell you something.I plan to invest in the hotels and entertainment centers in the . (13). 10 Day Erection Delay Sex Pills. The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for treating conventional diabetes may be beneficial. Pycnogenol treatment lowered the ACE-inhibitor dose required to control blood pressure, and lowered fasting glucose levels as well. (3), Ototoxicity is ear poisoning and can occur when exposed to certain drugs or chemicals, such as cisplatin, that damage the inner ear or the vestibulocochlear nerve. Learn about this tree-based pill and how it might be able to help you. Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease caused primarily by tobacco use. Its true. Pycnogenol suppresses inflammation and regulates the production of nitric oxide - a . Jonathan Ritter, PharmD, PhD (Pharmacology), Small molecule antioxidants (phenolic acids, catechin, and taxifolin) are quickly absorbed and begin to act in the body within 30 min, The remaining more complex antioxidants (long chains of procyanidins) reach the gut, where your, The microbiome-produced active compounds appear in blood 6 h later and remain for at least 14 h, Pycnogenol is standardized to contain 70 5% procyanidins, which should be on the label, Pycnogenol standardization doesnt determine other major active compounds, which can vary. Research into Pycnogenol has revealed some promising results in over 30 health conditions. In contrast, bleeding still occurred in the control group [61]. A study of 66 healthy adults found that Pycnogenol may reduce the number of leg cramps experienced [11]. All Pycnogenol-treated patients responded favorably in contrast to placebo treatment. Moreover, Pycnogenol lowered the chemical, leukotrienes responsible for asthma attacks. View as: Grid List. Start with a low dose so you can be sure it doesnt cause any side effects. The remaining compounds are phenolic acids, which may also have antioxidant activity [1, 2]. 7. Skin irritation. SelfDecode does not treat, diagnose or cure any conditions, Pycnogenol lotions applied postirradiation reduced this immunosuppression to 22% (0.05% Pycnogenol) and 13% (0.1% Pycnogenol). Pycnogenol lowered leukotrienes as well. In the study, the placebo group had higher IgE antibodies to the birch allergen than those who took Pycnogenol during the allergy season [17]. In mice, luteolin prevented inflammation and allergic response in the lungs and nose by inhibiting inflammatory cytokines: IL-4, IL-5, and IL-1 3 []. In another study, 45 men with ED were given 1.7 grams of L-arginine a day during the first month, 40 mg Pycnogenol twice daily during the second month, and the dose increased to three 40-mg Pycnogenol doses daily during the third month. Set Ascending Direction. In 24 people with early eye damage from diabetes, Pycnogenol improved vision, reduced eye swelling, and improved circulation in the eye after 2 months. Organika Pycnogenol 50mg 50 Tablets . Rare cases of liver disease. Chewing gum with Pycnogenol (2.5 mg/piece) for 4 weeks reduced bad breath and mouth bacteria in a trial of 22 people [57]. Eighty-six patients were treated either with Pycnogenol at 150 mg or 300 mg daily or the drugs diosmin and hesperidin (Daflon)at 1,000 mg daily for two months. No side effects were noted, unlike its synthetic counterpart. Information is shared for educational purposes only. So begins my look at the natural supplement, pycnogenol (French Maritime Pine Bark Extract)benefits. ", Mayo Clinic: High blood pressure (hypertension)., Panminerva Medica: "Pycnogenol improvements in asthma management. A 2015 review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity, diabetes, and high blood pressure. In 22 German heavy smokers, platelet aggregation was prevented by 500 mg of aspirin or 100 mg Pycnogenol. . 2005 - 2023 WebMD LLC. It comes from the bark of a European pine tree. Symptoms of menopausal syndrome, also known as climacteric syndrome, include: hot flashes; chills; headache; and depression. She loves communicating science and empowering people to achieve their optimal health. Our website services, content, and products are for informational purposes only. The supplement significantly reduced hot flashes, night sweats, mood swings, irregular periods, loss of libido, and vaginal dryness. returned. Pine bark extract may be the perfect treatment since its an antioxidant dynamo. Not bad. (8). Eye health. Learn about all the potential benefits of Pycnogenol and find out which ones are most supported by science. 7. There is currently insufficient evidence to determine what a safe and effective dose of lysine is for specific conditions. According to a Japanese study, the combination of Pycnogenolt and L-arginine may produce the results youre looking for, making the bedroom a much happier place. As a skin powder, however, you can use it safely for up to six weeks. For that reason, you should be careful taking pine bark if you have hypertension or diabetes. Pycnogenol (100 mg/day) may reduce hay fever symptoms, according to a clinical trial of 39 people. Two studies illustrate the possibilities: One was a randomized, double-blind, placebo-controlled, crossover study in which 26 asthmatic patients were given either a maximum of 200 mg a day of Pycnogenol or placebo for the first period of four weeks and then crossed over to the alternate treatment for the next four weeks. $109.99. In a study of 33 people with severe osteoarthritis, pycnogenol (200 mg/day) reduced inflammatory markers after 3 weeks. Thus, this powerful extract works as a natural ear infection remedy while improving balance and preventing hearing loss. Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. While much of this is positive, it will be a while before doctors routinely recommend this dietary supplement for these conditions. Another study of 47 women found that supplementing with 30 mg Pycnogenol twice daily for over 1 month may reduce menstrual pain [73]. Proper nutrition is essential for ADHD treatment. For most people, pine bark extract doesnt cause any side effects. It can also stabilize mast cells, which release histamine and trigger allergic reactions. Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. We avoid using tertiary references. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. Clearer skin, healthier hair there are a lot of claims about the health benefits of biotin. But a month after pycnogenol was stopped, the symptoms came back, suggesting that it may need to be used regularly to achieve the benefits [41]. For diseases of the retina, including those related to diabetes: 50 milligrams three times daily. These wounds occur most frequently in hospitals or in those with weakened immune systems, such as after surgery. If you are taking blood thinners, do not take pine bark extract or Pycnogenol unless approved by your doctor. Pycnogenol has given indications that it might be able to benefit heart and artery health, to include reducing high blood pressure. These benefits appeared to persist for some time even after stopping supplementation [72]. A study of 58 people with high blood pressure suggests that even lower doses (100 mg/day) may improve blood vessel health and reduce markers of high blood pressure (endothelin-1) after 12 weeks. Is Garcinia Cambogia Safe for Weight Loss? In the following sections, well discuss the common forms and dosages of Pycnogenol that are commercially available. Commonly called arthritis, osteoarthritis is caused when the cartilage on your joints begins to wear down. But, as you know, going for the natural approach can make a huge difference in overall health. While these results are promising, there isnt enough research to fully understand the effect of antioxidant levels on ADHD symptoms. High-dose Pycnogenol (360 mg/day) for 4 weeks had the same LDL-lowering benefits in another study of 40 people [32, 56]. The studies revealed that the sperm concentration greatly increased after about eight to 16 weeks of treatment, to include improved orgasmic function. Pycnogenol is officially extracted from the French maritime pine (Pinus pinaster), which grows in the southwest coast of France. The antibacterial activity was assessed indicating that the essential oil of pine bark, specifically the proanthocyanidins, were effective against P. aeruginosa, significantly inhibiting its growth. Any medication that you take, including herbal supplements, comes with certain risks. Speak with your doctor before supplementing. Pycnogenol is a patented extract of the French maritime pine bark (Pinus pinaster). , Improves Symptoms Associated With Menopause, A number of women experience physical discomfort due to symptoms of menopause. However, some of these other pine bark extracts can have different active compounds, which may affect their biological activity. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. There have been a variety of health benefits linked to beta glucan, specifically with the beta-1 3d glucan form which has more biological activity than other types of polysaccharides. Extracts can also be made from other pine barks, such as Pinus radiata, Pinus densiflora, Pinus thunbergii, and Pinus massoniana. The most effective blood sugar-lowering dose was 200 mg/day higher doses had no further benefit [33]. Pycnogenol led to a reduction of muscle cramps from 4.8 a week to 1.3 at week four. Today, I want to share with you my secrets to reduce sugar Top 7 Benefits of Green Tea: The No. Prunes and prune juice have many health benefits. Upset stomach. 1) Encourages Healthy Blood Pressure. Grape seed extract may have heart-health benefits. Pycnogenol may help with other conditions as well. The extract has been widely studied for the past 40 . We believe that the most accurate information is found directly in the scientific source. Studies have found that supplementing with pycnogenol effectively strengthens the blood vessels, stabilizing blood pressure. This supplement may also increase muscle endurance and performance after a single pre-exercise dose according to a study of 9 cyclists [12, 13]. Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT. However, with the addition of twice-daily Pycnogenol, normal erection increased to 80%, which further increased to 92.5% during the third month on thrice-daily Pycnogenol. DOI: Dvorkov M, et al. Its been noted that taking OPCs and vitamin C supplements at the same time could increase blood pressure if you have hypertension. Learn more. Pycnogenol, an extract of French maritime pine bark, helps the body fight normal aging by supporting vascular health and healthy circulation. Another one of its exemplary effects is helping manage blood pressure levels. The following purported benefits of Pycnogenol are only supported by limited, low-quality clinical studies. (14, 15). However, these studies appear to be methodologically sound and reliable, with no blatant errors in the study design and data collection. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. The standard dose appears to be 100-200 mg/day. Circulation and Jet Lag on Long Flights. L-arginine is more effective when paired with L-citrulline or pycnogenol to combat erectile dysfunction and improve exercise performance. There havent been any studies looking at long-term liver damage. So it . Researchers suggest that it may have stronger benefits than elastic compression stockings. Infants and children may not be able to synthesize enough of it, but it is present in many protein-rich . In one clinical trial of 156 osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. In addition to general healthy eating, some specific vitamins and minerals may help improve ADHD. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. The 2012 study on the anti-aging benefits of Pycnogenol is commonly-cited by anti-aging supplement manufacturers. Since components of Pycnogenol can be modified during digestion and absorption as well as by the liver, diseases that affect the gut or liver may increase or decrease its effects [84]. One study involved a four-week treatment period followed by one week of no treatment or observation period. Theres some evidence that Pycnogenol acts similar to a sustained-release formulation. It also reduced the size of scars. Along with the rest of the crew, he developed symptoms of vitamin-C deficiency. Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. The flesh of the grape contains approximately 1/20th-1/100th of the total antioxidant capacity of the seed or the skin. New research has shown promising results for those dealing with erectile dysfunction (ED) and diabetes. However, it's always a good idea to start with a low dose so you can monitor how your body responds. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. People who use the supplement along with their traditional medication usually take smaller doses than those who only take the supplement. The researchers concluded that pine bark extract may increase production of hyaluronic acid and collagen, which are both found in many popular antiaging products. In contrast, almost 20% of the participants on inhalers alone had to increase their dosage. Pine bark extract offers some amazing benefits since its so high in powerful antioxidants. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. The treatment was four 50 mg capsules of Pycnogenol. Are there any risks to taking it? 3. Reduces Pain. Both supplements are antioxidants, which have been shown to help with blood flow and erectile function. 2. Clinical research suggests that Pycnogenol is possibly effective for improving athletic performance. Some of the top lutein-rich foods to include in your diet are dark leafy greens like spinach and kale, broccoli . (2012). But what are its health benefits? Some risks associated with Pycnogenol include:, Pycnogenol and other maritime tree barks have not been studied as extensively as traditional medicine. In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. Children who took a pine bark extract supplement for one month had healthy antioxidant levels. In 1534, a French ship led by the famous explorer Jacques Cartier became stranded in ice near Quebec, Canada. Studies on human subjects have reported few side effects - even . It is standardized to contain 65-75% procyanidins, a class of polyphenols and flavonoids like those found in blueberries, wine, grape skin, citrus, and cocoa. In a good-quality study, 100 patients with osteoarthritis of the knee were treated for three months either with 150 mg of Pycnogenol a day or placebo. The researchers of the study propose that pycnogenol may reduce pain and cramps during retraining and rehabilitation in people with blood vessel problems [11]. Pine bark extract can be found in liquid, tablet or capsule form containing 85 percent to 90 percent OPCs. From diabetes and sexual function to sports performance and beautiful skin, pine bark extract may be worth exploring to provide results youre looking to achieve. A combination product with Pycnogenol (Lady Prelox) improved sexual function in a clinical trial of 83 healthy postmenopausal women after 8 weeks. This article reviews tongkat ali, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Results showed that one month of Pycnogenol led to a significant reduction of hyperactivity with improvement in attention and visual-motor coordination and concentration, as compared to no positive effects in the placebo group. If you knew you could resolve your erectile dysfunction and, therefore, naturally remedy impotence issues, wouldnt you? A 2006 study found that children who took a daily pine bark extract supplement for four weeks had significantly lower levels of hyperactivity. Its best to check with your doctor about the dosage, based on the symptoms you have and other possible conditions, prior to taking either pine bark extract or Pycnogenol. Another 2006 study examined the effects of the antioxidant activity of pine bark extract on oxidative stress, which is thought to be one of the nongenetic factors contributing to ADHD. The review found evidence that pine bark extract may: Similar to its neuroprotective benefits, the metabolic benefits of pine bark extract seem to be related to its antioxidant and anti-inflammatory properties. Once youre sure that you dont have any negative reactions, you may be able to increase your dosage according to the label. Video: Why You Need Zinc and Where to Find It. The effect of polyphenolic extract from pine bark, Pycnogenol on the level of glutathione in children suffering from attention deficit hyperactivity disorder (ADHD) [Abstract]. Results failed to show any efficacy of Pycnogenol or methylphenidate when compared to placebo. Pycnogenol significantly improved the heavy feeling as well as the swelling. Side Effects of Pycnogenol. In addition to OPC, grape seed extract contains linoleic acid, flavonoids and phenolic procyanidins that help protect and strengthen capillaries, blood vessels, veins and arteries, which can then improve blood circulation.
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